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Sep 17, 2017; Pittsburgh, PA, USA; Pittsburgh Steelers head coach Mike Tomlin looks on against the Minnesota Vikings during the fourth quarter at Heinz Field. The Steelers won 26-9.

The Buffalo Bills will try to win their first playoff game since the 1995 season when they host the Indianapolis Colts on Saturday in the 2021 NFL Playoffs. The Bills have not won a postseason game since beating Miami, 37-22, in a Wild Card game on Dec. 30, 1995. Since then, they have lost six consecutive playoff games by an average of 7.5 points. Buffalo's postseason drought is the third longest active streak in the NFL, so can you trust the Bills with your NFL picks this week?

On Saturday, the Bills (13-3) will take on an 11-5 Colts team that is returning to the playoffs after a one-year absence. Buffalo is listed as a 6.5-point favorite in the latest NFL odds from William Hill Sportsbook. The game is one of six matchups on the Wild Card schedule, but which teams should you back with your NFL bets and NFL parlays? Before making any NFL Wild Card picks or playoff predictions, see the NFL best bets from legendary handicapper Hammerin' Hank Goldberg over at SportsLine.

A beloved national treasure, Hammer enters the postseason on an extended heater: Over the final 10 weeks of the 2019 season and through the 2020 regular season, he is an incredible 47-30-1 on his NFL best bets, a 60 percent cash rate. He's 9-6-1 on his best bets the past six weeks.

This is the same prognosticator who enjoyed 15 winning seasons in his 17-year ESPN run. In 2017, Hammer competed against 10 top handicappers in the Las Vegas Review-Journal's NFL Challenge and beat them all, finishing 50-29-6 on against-the-spread NFL picks. Anyone who has followed him is way up.

Now, Hammer has locked in three confident best bets for Wild Card weekend. If you parlay his picks, you could be looking at a 6-1 payout. You can only see them here.

Top Wild Card NFL expert picks

After thoroughly examining the six games on Wild Card weekend, Hammer jumped on the Steelers (-6) to cover against the Browns. Pittsburgh (12-4) rode a devastating pass rush that led the league in sacks (56) to the third best record in the AFC. Last week, several key starters, including quarterback Ben Roethlisberger, were finally able to get a much-needed week off since COVID-19 issues and schedule juggling forced the team to go without one since Week 4.

On Sunday, Cleveland will be the team that's most impacted by COVID-19. Coach Kevin Stefanski, the primary play-caller, will not be on the sideline after testing positive for the virus. In addition, the COVID-19 issues forced the Browns to close their team facility and have a virtual walk-through earlier this week after recent positive COVID-19 tests.

How to make Wild Card NFL parlays

Best Parlay Picks This Week

Hammer, who has inside sources throughout the league, also jumped on two other matchups: Washington vs. Tampa Bay and Titans vs. Ravens. Hammer says one of those teams 'wins as it pleases,' leading to an easy cover. You can only see his best bets here.

Best Parlay Bets Today

What are Hammer's top Wild Card weekend picks? And which side of Washington vs. Tampa Bay and Tennessee vs. Baltimore do you need to jump on? Visit SportsLine now to see Hammerin' Hank Goldberg's Wild Card best bets, all from the legendary handicapper on a 47-30-1 heater, and find out.